Table 1.

Acronyms used in this report.

Acronym	Full Name
2′OMe	2′-O-methyl ribose sugar modification
3′ss	3′ splice site
3UP8	8mer ASO that partially targets ISS-N1
5′ss	5′ splice site
A3S	Alternative 3′ splice site usage
A5S	Alternative 5′ splice site usage
Anti-N1	20mer ASO targeting ISS-N1
ASO	antisense oligonucleotide
EIN	Increased exon inclusion
ESK	Increased exon skipping
F14	14mer ASO that targets ISS-N1
F18	18mer ASO that targets ISS-N1
HiA	High concentration (100 nM) of Anti-N1
IRM	Improved intron removal
IRT	Increased intron retention
ISO	ISS-N1 targeting splice switching ASO
ISS-N1	Intronic splicing silencer N1
L2FC	log(2) fold change
LoA	Low concentration (5 nM) of Anti-N1
MOE	2′-O-methoxyethyl ribose sugar modification
MXE	Mutually exclusive exons and/or mixed events