Figure 1.

Cell metabolic activity (%) of MSCs grown on the scaffold cultured in serum-free medium and exposed to different doses of Lyosecretome over time. Untreated cells (0 Lyosecretome cell equivalents and no FBS) at the 5 day-time point were considered control. Multifactor ANOVA (time and concentration, mean values ± LSD, n = 3) was used. Both time and concentration were significant (p < 0.0001 and p = 0.0004, respectively). Different letters indicate a significant difference between the means (p < 0.05), while the same letters indicate no significant difference between the means (p > 0.05).