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. 2021 Aug 5;22(16):8430. doi: 10.3390/ijms22168430

Table 7.

EV-associated markers shared among different cancers.

miRNAs Tumor Up/Downregulation References
miR-21 Ovarian cancer
Prostate cancer
Bladder cancer
HPV-related cervical cancer
Breast cancer
Upregulated
Upregulated
Upregulated
Upregulated
Upregulated
Upregulated
Upregulated
[46,62,86,88,118,123,124,160]
miR-21-5p Urothelial carcinoma
miR-145 Ovarian cancer
Prostate cancer
Upregulated
Upregulated
[130,163,167]
miR-126 Ovarian cancer
Bladder cancer
Downregulated
Ratio
[87,144]
miR-92a
miR-92a-3p
Ovarian cancer
Breast cancer
Cervical cancer
Upregulated
Upregulated
Downregulated
Upregulated
[47,65,160]
miR-92a-2-5p Breast cancer
Let7b
Let7c
Let7i
Ovarian cancer
Prostate cancer
Breast cancer
Downregulated
Upregulated
Downregulated
[33,123,165]
miR-320
miR-320a
Ovarian cancer
Breast cancer
Downregulated
Upregulated
[33,160]
miR-375 Bladder cancer
Prostate cancer
Ovarian cancer
Upregulated
Upregulated
Upregulated
[85,123,124,168]
miR-720 Ovarian cancer
Bladder cancer
Downregulated
Upregulated
[88,165]
miR-205
miR205-5p
Ovarian cancer
Ovarian cancer
Bladder cancer
Up or Downregulated
Upregulated
Upregulated
[88,144,165,167]
miR-200
miR-200 a/b/c
miR-200c-3p
Prostate cancer
Ovarian cancer
Bladder cancer
Upregulated
Upregulated
Upregulated
[88,124,144,160,161,163]
miR-1290 Ovarian cancer
Prostate cancer
Upregulated
Upregulated
[126,168]
miR-141 Prostate cancer
Ovarian cancer
Upregulated
Upregulated
[127,133,144]
miR-373 Breast cancer
Ovarian cancer
Upregulated
Upregulated
[49,160]
miR-30-c-5p
miR-30d
Renal cell carcinoma
Ovarian cancer
Downregulated
Downregulated
[70,165]
miR-1246 Breast cancer
Prostate cancer
Upregulated
Upregulated
[46,135]
miR-19
miR-19b-3p
miR-19b1-5p
Prostate cancer
Breast cancer
Bladder cancer
Upregulated
Upregulated
Upregulated
[47,89,129]
miR-146a Bladder cancer
HPV-related cervical cancer
Upregulated
Upregulated
[62,85]
miR-20a-5p
miR-20b-5p
Cervical cancer
Breast cancer
Downregulated
Upregulated
[47,65]
miR-423
miR-423-3p
Breast cancer
Cervical cancer
Downregulated
Downregulated
[33,65]
LncRNAs
MALAT1 Bladder cancer
Cervical cancer
Upregulated
Upregulated
[29,63]
HOTAIR Cervical cancer
Bladder cancer
Upregulated
Upregulated
[63,90]
Proteins
B-catenin
D-catenin
Ovarian cancer
Prostate cancer
Upregulated
Expressed
[104,140]
EpCAM Ovarian cancer
Breast cancer
Upregulated
Upregulated
[35,57,148,149,150]
FGA Bladder cancer
Ovarian cancer
Upregulated
Upregulated
[77,153]
FASN Prostate cancer
Ovarian cancer
Expressed
Expressed
[105,149]
LTF Prostate cancer
Ovarian cancer
Expressed
Upregulated
[105,155]