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. 2021 Aug 6;22(16):8456. doi: 10.3390/ijms22168456

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Survival rates and chIFITM1 expression quantification. (A) Percentage survival rates of RCASBP(A)-chIFITM1 and RCASBP(A)-WT challenged chicks with clinical and sub-lethal doses of H5N1 HPAIV compared to mock inoculated chicks (negative and positive control groups). (B) Expression of chIFITM1 in HPAI H5N1 challenged transgenic chickens with RCASBP(A)-chIFITM1 compared to transgenic chickens (RCASBP(A)-WT) and non-transgenic chicken (mock inoculated neg. ctrl), asterisks indicate significant difference.