Figure 2.

The effect of two-week treatment with iloperidone on the protein levels of CYP1A, CYP2B, CYP2C11, CYP3A, and CYP2E1 enzymes in rat liver microsomes. Microsomal proteins (10 μg) were subjected to the Western immunoblot analysis. The results are presented as representative blots from six (for the control and for iloperidone treatment) separate rats per treatment. The data are expressed as the mean ± S.E.M. (n = 12). Statistical significance was assessed by Student’s t-test and marked as * p < 0.05, ** p < 0.01, **** p < 0.0001, compared with the control.