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. 2021 Aug 9;22(16):8547. doi: 10.3390/ijms22168547

Figure 6.

Figure 6

AVR-48 promotes vascular development. (A) Representative immunofluorescent lung sections showing vascular development. vWF, a marker for blood vessels, is severely disrupted in BPD, while after treatment with AVR-48 there is significant improvement. (B) Representative Western blotting showing Ang2 is restored after treatment with AVR-48, in the BPD group. The top right panel shows quantification of the number of blood vessels while the bottom right panel shows densitometric quantification for Ang2. Scale bar 100 µm; * p < 0.05; ** p < 0.01; *** p < 0.001; vWF: von Willebrand factor; Ang2: angiopoietin 2; RA: room air; BPD: bronchopulmonary dysplasia; HPF: high power field; n = 3–5.