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. 2021 Aug 6;22(16):8481. doi: 10.3390/ijms22168481

Figure 3.

Figure 3

sq-RT-PCR analysis of YY1 putative transcriptional targets within the apoptotic pathway. Gel electrophoresis results. In CRC cells panel (HCT-116, Caco-2, HT-29 SW620); HT-29 (CTRL, KD-01, KD-02); SW620 (CTRL, KD-01, KD-02). YY1 (blue) is expressed in all four cell lines. BCL2L15 (green) is selectively expressed in HT-29 and SW620 cells and not detected in HCT-116 and Caco-2 cells. Upon YY1 knock-down (blue boxes), BCL2L15 is downregulated in both HT-29 and SW620 CRC cells (both KD-01 and KD-02, green boxes).