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. 2021 Aug 9;22(16):8566. doi: 10.3390/ijms22168566

Table 2.

Proteins of the spleen proteome (listed in Table 1) reported in the literature as being associated with curcumin’s therapeutic effects.

Authors (Year) Biological Model/Topic
AHR
(Ahr)
Ciolino et al. [12] MCF-7 Human breast carcinoma cells
Rinaldi et al. [13] Human oral squamous cell carcinoma cells
Nishiumi et al. [14] Mouse hepatoma Hepa-1c1c7
Choi et al. [15] Hep3B, MCF-7, HEK 293 human cells…
Garg et al. [16] Mice (in vivo)
Cifti et al. [17] Rats (in vivo)
Singh et al. [18] Drosophila larvae
Mohammadi-Bardbori et al. [19] Human hepatoma
Nakai et al. [20] Mouse hepatoma
ANXA5
(Anxa5)
Kam et al. [21] EAhy926 human endothelial cells
CO9
(C9)
Jacob et al. [22] Mice (in vivo)
GRP78
(Hspa5)
Ravindranathan et al. [23] Colorectal cancer cells
LEG1
(Lgals1)
Rabinovitch et al. [24] Normal rat T cells (from spleen)
Brandt et al. [25] Human leukemic T cells
MVP
(Mvp)
Thiyagarajan et al. [26] Y79 human retinoblastoma cells
PDCD4
(Pdcd4)
Mudduluru et al. [27] Rko and HCT116 human colorectal cancer cells
Yang et al. [28] DU145 human prostate cancer cells, B16 murine melanoma cells
Chen et al. [29] Review: microRNAs regulation
Lelli et al. [30] Review: melanoma
Tan et al. [31] C6 rat experimental glioblastoma
Shakeri et al. [32] Review: microRNA-21
PDIA1
(P4hb)
Ouyang et al. [33] Mouse intestinal mucosa (in vivo)
PSB10
(Psmb10)
Wang et al. [34] MCF-7 Human breast carcinoma cells
RHOA
(Rhoa)
Zhang et al. [35] Lu1205 and A375 human melanoma cells
Qin et al. [36] HSC-T6 rat cells, rat liver fibrosis (in vivo)
Wang et al. [37] HMrSV5 human peritoneal mesothelial cells
Gallardo et al. [38] MCF-10F and MDA-MB-231 human breast cancer cells
SPRC
(Sparc)
Kilian et al. [39] PC-3 human prostate cancer cells + xenografts in CD-1 mice (in vivo)
Wang et al. [34] MCF-7 Human breast carcinoma cells
STIM1
(Stim1)
Shin et al. [40] HEK293 human embryonic kidney cells
TAGL2
(Tagln2)
Ma et al. [41] CAL 27 human tongue cancer cells