Table 3.
Early (1, 8 DPL peak) profile of deregulated pathways in cerebral Motor Cortex.
| NAME | ID | SIZE | ES | NES | NOM.p.val | FDR.q.val | FWER.p.val |
|---|---|---|---|---|---|---|---|
| 1 DPL | |||||||
| GOBP_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | GO:0008284 | 21 | −0.55747 | −2.01551 | 0 | 0.074913 | 0.441 |
| GOBP_ACTIVATION_OF_MAPK_ACTIVITY | GO:0000187 | 6 | −0.8384 | −2.01837 | 0 | 0.080351 | 0.431 |
| GOBP_REGULATION_OF_CELL_CELL_ADHESION | GO:0022407 | 9 | −0.75613 | −2.06508 | 0.004202 | 0.055305 | 0.294 |
| GOBP_POSITIVE_REGULATION_OF_LOCOMOTION | GO:0040017 | 11 | −0.70714 | −2.08796 | 0 | 0.049878 * | 0.249 |
| GOBP_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | GO:0043406 | 6 | −0.8384 | −2.08928 | 0 | 0.056779 | 0.248 |
| GOBP_OSSIFICATION | GO:0001503 | 9 | −0.77164 | −2.11155 | 0 | 0.0504 * | 0.192 |
| GOBP_POSITIVE_REGULATION_OF_MAPK_CASCADE | GO:0043410 | 9 | −0.76861 | −2.15364 | 0 | 0.039986 * | 0.13 |
| GOBP_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | GO:0010638 | 10 | −0.74741 | −2.15712 | 0.002299 | 0.047046 * | 0.122 |
| GOBP_REGULATION_OF_PEPTIDE_TRANSPORT | GO:0090087 | 10 | −0.73899 | −2.15933 | 0 | 0.060828 | 0.118 |
| GOBP_MUSCLE_CELL_PROLIFERATION | GO:0033002 | 8 | −0.79286 | −2.16342 | 0 | 0.089101 | 0.115 |
| GOBP_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | GO:0032101 | 15 | −0.68666 | −2.28367 | 0 | 0.037286 * | 0.025 |
| 8 DPL | |||||||
| REACTOME_NGF_STIMULATED_TRANSCRIPTION | R-RNO-9031628 | 9 | −0.70493 | −1.96836 | 0.006316 | 0.096106 | 0.478 |
| GOBP_MUSCLE_TISSUE_DEVELOPMENT | GO:0060537 | 11 | −0.67464 | −2.0182 | 0.002304 | 0.091098 | 0.334 |
| GOBP_POSITIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION | GO:0008284 | 21 | −0.57177 | −2.03369 | 0 | 0.09632 | 0.289 |
| GOBP_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | GO:0009891 | 27 | −0.53552 | −2.05973 | 0.002088 | 0.099952 | 0.235 |
* FDR ≤ 0.05.