Figure 9.

Intracellular expression of inflammation-specific miR-155 (A) was upregulated in response to the exposure of HCPEpiCs to IVH-III (light red column) or IVH-IV (red column) CSF samples for 24 h. Conversely, miR-223 (B) and miR-181b (C) levels were downregulated by the inflammatory stimulus compared to cells treated with non-IVH CSF samples (blue column). Mean ± SEM are depicted, n = 7–8/group. The ANOVA test with Bonferroni’s multiple comparison test was used for the comparisons. Abbreviations: CSF, cerebrospinal fluid; HCPEpiCs, human choroid plexus epithelial cells; IVH, intraventricular hemorrhage; and miRNA, microRNA.