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Variability in FcɣR expression on circulating monocytes (CD14+) in the blood of patients with metastatic breast cancer (mBC). CD64, CD32, and CD16 FcɣRs were evaluated in each patient. Open circles and bars represent individual patient results and mean, respectively. This high interpatient variability in the expression of FcɣRs on MPS cells in blood in consistent with the interpatient variability in the PK of mAbs and ADCs [143].
