Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 13;22(16):8693. doi: 10.3390/ijms22168693

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Bazedoxifene inhibited migration, invasion, and colony formation of cervical cancer cells. (A) Migration assay was used to determine migration of SiHa, HeLa, CaSki cells after 0, 24, and 48 h of Bazedoxifene treatment (*, p < 0.05; **, p < 0.01; ***, p < 0.001 vs. control). (B) Matrigel invasion assay was used to determine invasion of SiHa, HeLa, and CaSki cells after 48 h of Bazedoxifene treatment. (C) Colony formation assay was conducted on SiHa, HeLa, and CaSki cells treated with Bazedoxifene for 48 h. Clones were grown by reseeding at 1000 cells per well and incubating for 2–3 weeks. Scale bar, 100 μm. Bars indicate mean ± standard deviation of three independent experiments performed in triplicate (*, p < 0.05; **, p < 0.01; ***, p < 0.001 vs. control). B: Bazedoxifene.

Bazedoxifene inhibited migration, invasion, and colony formation of cervical cancer cells. (A) Migration assay was used to determine migration of SiHa, HeLa, CaSki cells after 0, 24, and 48 h of Bazedoxifene treatment (*, p < 0.05; **, p < 0.01; ***, p < 0.001 vs. control). (B) Matrigel invasion assay was used to determine invasion of SiHa, HeLa, and CaSki cells after 48 h of Bazedoxifene treatment. (C) Colony formation assay was conducted on SiHa, HeLa, and CaSki cells treated with Bazedoxifene for 48 h. Clones were grown by reseeding at 1000 cells per well and incubating for 2–3 weeks. Scale bar, 100 μm. Bars indicate mean ± standard deviation of three independent experiments performed in triplicate (*, p < 0.05; **, p < 0.01; ***, p < 0.001 vs. control). B: Bazedoxifene.