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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Pediatr Pulmonol. 2021 Jul 16;56(9):2868–2878. doi: 10.1002/ppul.25559

Figure 3.

Figure 3.

A. Clustering of 97 MRSA isolates based upon accessory gene content. Accessory genes were obtained from 25 reference genomes. Each row represents a CF MRSA isolate, and numbers are given at right. Each column is one of 1625 accessory genes; black color indicates detection of the accessory gene. The isolates clustered into three groups named at left. Clusters assigned on the basis of accessory genes matched the results from SNP-based clustering. Cluster A included ST5 and ST105 isolates. Cluster B included ST8 and related isolates. Cluster C included distantly related S. aureus, including a livestockassociated ST398 strain (#24). B. Unequal distribution of MRSA clusters by birth year. Cluster A was widely distributed across ages, whereas Cluster B was limited to more recent birth years. * P = 0.0009 by Wilcoxon rank sum test.