Table 2.
Characteristic | Cluster A N = 20 | Cluster B N = 12 | P |
---|---|---|---|
Age, years† Median [IQR] | 13.6 [10.4 – 16.4] | 11.1 [9.0 – 17.1] | 0.50* |
MRSA acquisition date, Median [IQR] | 09/2009 [7/2007 – 02/2015] | 08/2013 [12/2011 – 03/2015] | 0.14* |
Female Sex | 10 (50%) | 4 (33%) | 0.48‡ |
Genotype | 0.62‡ | ||
ΔF508/ΔF508 | 11 (55%) | 6 (50%) | |
ΔF508/other | 7 (35%) | 6 (50%) | |
Other/other | 2 (10%) | 0 | |
Sputum production, N (%) | 15 (75%) | 10 (83%) | 0.68‡ |
P. aeruginosa N (%) | 11 (55%) | 6 (50%) | 1.0‡ |
Spirometry performed, N (%) | 19 (95%) | 12 (100%) | 1.0‡ |
Medications in 2017 | |||
Trimethoprim/Sulfamethoxazole | 12 (60%) | 10 (83%) | 0.25‡ |
Linezolid | 14 (70%) | 5 (42%) | 0.15‡ |
Doxycycline | 10 (50%) | 1 (8.3%) | 0.02‡ |
Vancomycin IV | 9 (45%) | 6 (50%) | 1.0‡ |
Tobramycin inhaled | 14 (70%) | 7 (58%) | 0.70‡ |
Ciprofloxacin | 9 (45%) | 4 (33%) | 0.72‡ |
Azithromycin | 19 (95%) | 11 (92%) | 1.0‡ |
Ivacaftor | 2 (10%) | 2 (17%) | 0.62‡ |
Lumacaftor/Ivacaftor | 11 (55%) | 5 (42%) | 0.72‡ |
Age determined on July 1, 2017. No subjects had lung transplant or CFTR related metabolic syndrome. P values determined by
Wilcoxon rank sum test or
Fisher’s exact test.