Table 1.
Disintegration time of the theophylline tablets covered with the PSG prepared from carboxymethyl cellulose (CMC), low molecular weight chitosan (LMCS), and high molecular weight chitosan (HMCS), offering proper viscosity and flow ability.
| Ingredient | Formulation (% w/w) | ||
|---|---|---|---|
| CMC Gel | LMCS Gel | HMCS Gel | |
| Carboxymethyl cellulose | 4 | - | - |
| Low molecular weight chitosan | - | 5 | - |
| High molecular weight chitosan | - | - | 6.25 |
| Glycerin | 1 | 6 | 4 |
| Purified water | qs | qs | qs |
| Tablet disintegration time (s) | 10.10 ± 1.37 | 10.72 ± 4.19 | 6.70 ± 3.22 |