Table 2.
f1 (similarity factor) and f2 (dissimilarity factor) of the theophylline tablets covered with several gel type compared with the plain tablet.
|
f1: Similarity Factor (Limit: 50–100) |
f2: Dissimilarity Factor (Limit: 0–15) | Dissolution Difference Factor (f1 − f2) | |
|---|---|---|---|
| Theophylline tablet with reference gel product |
45 | 12 | 33 |
| Theophylline tablet with carboxymethyl cellulose |
37 | 19 | 18 |
| Theophylline tablet with low molecular weight chitosan |
43 | 13 | 30 |
| Theophylline tablet with high molecular weight chitosan |
40 | 16 | 24 |