Table 5.
Summary of non-coding variants associated with cancer clinomics.
| SNP ID | Target Locus | Clinical Trait | Cancer Type | Citation |
|---|---|---|---|---|
| rs291593 | DPYD 3′UTR | Drug toxicity | Breast cancer | [316] |
| rs3209896, rs1824125 | AKR1C3 3′UTR, PGR 3′UTR | Progression-free Survival | ||
| rs1054899 | ALDH5A1 3′UTR | Chemotherapeutic response to FAC | ||
| rs7756222, rs9487402 | SLC22A16 3′UTR | Overall survival | ||
| rs13230517 | RP11-3N2.1 promoter | Cancer Risk | Colorectal cancer | [317] |
| rs531564 | pri-miR-124 | Lymph node metastasis | ||
| rs3741219, rs2910164, rs4938723 | H19 lncRNA, hsa-mir-146a, hsa-mir-34b/c | Cancer risk | Hepatocellular carcinoma | [318] |
| rs11614913, rs2292832 | hsa-mir-196a-2, hsa-mir-149 | Cancer risk | HBV-related HCC | [319] |