Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sequence alignment of human OATP1B1 and OATP1B3. Twelve putative transmembrane domains are under the black dotted lines. The specific domains critical for transport specificity are under the red dotted lines. The amino acid residues the are presumably important for CCK-8 are labeled with a blue star. The conserved amino acid residues between OATP1B1 and OATP1B3 are in red. Three GxxxG motifs associated with oligomerization are boxed in red.
