Table 2. Clinical characteristics of patients with heart failure, according to phenotype HFpEF, HFmrEF, or HFpEF.
| HF-free (n=509) | HFrEF (n=11) | HFmrEF (n=10) | HFpEF (n=30) | Overall | HFrEF vs. HFmrEF | HFpEF vs. HFmrEF | HFrEF vs. HFpEF | |
|---|---|---|---|---|---|---|---|---|
| Ejection fraction, % | 61(58-65) | 29(23-33) | 43.5(41-48) | 59.5(56.7-64.2) | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| Mean E/e' ratio, (±SD) | 6.5(5.4-7.8) | 9.6(7.5-17) | 8.3(6-9.1) | 7.9(6.1-12.1) | <0.0001 | 0.149 | 0.791 | 0.162 |
| LAVI, ml/m2, (±SD) | 20.9(17.3-24.5) | 38.6(26.8-65.9) | 30.5(18.9-42.2) | 29.4(24.3-41.8) | <0.0001 | 0.231 | 0.607 | 0.188 |
| LVMI, g/m2, (±SD) | 89.3(76.5-102.8) | 160.2(113.1-187.3) | 119.0(102.9-154.0) | 104.2(76.9-127.1) | <0.0001 | 0.091 | 0.123 | 0.002 |
| EDVI, ml/m2, (±SD) | 62.8(54.5-71.2) | 106.0(82.5-150.3) | 93.8(75.6-114.3) | 68.7(54.2-76.2) | <0.0001 | 0.360 | <0.0001 | 0.001 |
E: early mitral inflow velocity; E´: mitral annular early diastolic velocity; EDVI: end-diastolic volume index; HF: heart failure; HFmrEF: heart failure with mid-range ejection fraction; HFpEF: heart failure with preserved ejection fraction; HFrEF: heart failure with reduced ejection fraction; LAVI: left atrial volume index; LVMI: left ventricular mass index. Data are shown as median and interquartile range (25% and 75%); (*) overall p value were calculated using the Kruskal-Wallis test; differences between HFpEF, HFmrEF and HFrEF were calculated using the Mann-Whitney test.