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. 2021 Aug 16;22(16):8791. doi: 10.3390/ijms22168791

Figure 7.

Figure 7

Schematic of the mechanisms by which RA reduces cellular lipid contents and increases cholesterol efflux by macrophages. Rosmarinic acid inhibits foam cells formation by decreasing lipid contents in macrophages and induces cholesterol efflux via upregulating ABC transporters. ↑; increase, ↓; decrease, T; inhibit.