Table 5.
Author | Year | Sample Size (n) | Sample Type | Sampling | Time of the Day (h) | Time of Collection |
Preparation | Method | Intra, Inter Assay (%CV) | LOD (pg/mL) |
R (%) | Concentration (pg/mL) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Ilcol et al. [120] | 2008 | 160 | C, M | 3 h after breakfast |
Morning | 1–3, 4–14, 15–30, 30–90, 91–180 d |
SM | ELISA | <5, 8 | 0.16 | - | 1710 ± 68 |
Savino et al. [37] | 2012 | 23 | - | - | - | <6 mo | SM | ELISA | <5, 6.8 | 6 | - | 180 (400) |
Andreas et al. [46] | 2016 | 120 | C, M | 1 h after feed, pre- and post-feed, protease inhibitors | 10:00–13:00 | 1 wk, 3 mo |
SM | Multiplex assay | 3, 4 | 1.3 | - | 1 wk, pre-feed, 924.9 (295.9); post-feed, 967.4 (317.0) 3 mo, pre-feed, 792.5 (224.4); post-feed, 733.9 (238.9) mean (SEM); ng/mL |
Data reported as mean ± SD or median (IQR) unless specified. C, colostrum milk; CV %, coefficient variation percentage; d, day; ELISA, enzyme-linked immunosorbent assay; LOD, limit of detection; M, mature milk; mo, month; R %, recovery of analyte percentage; SM, skim milk; wk, week.