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. 2021 Aug 13;22(16):8708. doi: 10.3390/ijms22168708

Table 7.

Studies examining human milk apelin.

Author Year Sample Size (n) Sample Type Sampling Time of
the Day (h)
Time of
Collection
Preparation Method Intra, Inter Assay (%CV) LOD R (%) Concentration
(ng/mL)
Aydin [102] 2010 20 C, M - 08:00 1–4 mo WM EIA - - - GDM,
C, apelin-12, 2.9 ± 0.6
C, apelin-36, 3.2 ± 0.7
M, apelin-12, 3.6 ± 1.2
M, apelin-36, 4.4 ± 1.4
CTL,
C, apelin-12, 4.3 ± 1.2
C, apelin-36, 4.9 ± 2
M, apelin-12, 5.4 ± 1.8
M, apelin-36, 6.2 ± 1.9

Data reported as mean ± SD. C, colostrum milk; CTL, control group; CV %, coefficient variation percentage; EIA, enzyme immunoassay; GDM, gestational diabetes mellitus; LOD, limit of detection; M, mature milk; mo, month; R %, recovery of analyte percentage; WM, whole milk.