Figure 1.

SSM melanoma and pagetoid Spitz nevus (hematoxylin, phloxin, safranin stain). (A): Low-magnification silhouette of SSM, 14-year-old: mainly junctional disorganized melanocytic proliferation. (B): Close-up view showing dispersed junctional nests. Ascent of isolated cell. Numerous lymphocytes and melanophages clutter the upper dermis. (C): Invasive melanoma with “pseudo-maturation” and mitotic figure (arrow). (D): Large, junctional, foamy melanocytes. (E): Low-magnification silhouette of a pagetoid Spitz nevus, 6-year-old. Epidermal hyperplasia encasing numerous small nests with a regular distribution. (F,G): Close-up view with isolated cells and small nests. An important pericellular retraction is seen. Ascent of small, isolated cells. Arborescent vascular structure in the upper dermis surrounded by small lymphocytes.