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. 2021 Aug 25;9(3):56. doi: 10.3390/medsci9030056

Table 3.

Insulin BBB pharmacokinetics in the absence of serum factors following chronic rapamycin treatment based on Figure 8.

Sex Treatment Ki (µL/g∙min) Ki p-Value r Vi (µL/g) Vi p-Value
Male Vehicle 1.32 ± 0.42 0.97 0.766 9.6 ± 1.3 0.122
Rapamycin 1.35 ± 0.53 0.672 8.0 ± 1.7
Female Vehicle 0.90 ± 0.83 (ns) 0.35 0.378 11.5 ± 2.7 0.860
Rapamycin 1.89 ± 0.63 0.726 8.3 ± 2.1