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. 2021 Aug 16;22(16):8777. doi: 10.3390/ijms22168777

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Gene expression of (A) IL6, (B) CXCL8, (C) MKI67, (D) RELA, (E) ERK1 and (F) ERK2 of FTC-133 follicular thyroid cancer cells grown in space on the International Space Station for 5 and 10 days. * p < 0.05 versus 1g ground control cells. Values are presented as the mean ± standard deviation in percent of 1g ground controls, which was fixed as 100% for each condition. AD corresponds to adherent cells; MCS corresponds to multicellular spheroids. 5-day spaceflight/1g ground control samples, n = 3; 10-day spaceflight samples/1g ground control, n = 2.