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. Author manuscript; available in PMC: 2022 Aug 23.
Published in final edited form as: Dev Cell. 2021 Aug 23;56(16):2381–2398.e6. doi: 10.1016/j.devcel.2021.07.017

Figure 6 -. Linking precursors and progeny.

Figure 6 -

(A) Correlation of gene expression between adult mouse clusters and human developmental clusters in S-shaped body. (B) Proposed model for relationships between S-shaped body precursors and adult nephron cell-types based on correlation analyses. (C) Expression of transcription factors in the adult mouse nephron. (D) Immunofluorescent stains for transcription factors in human nephrons. White arrowheads indicate putative macula densa precursors. Schematics indicating the area each protein is detected in S-shaped body nephrons. Schematics also summarize data in Supplementary figure 11. (E-F) Immunofluorescent labelling of human nephrons during serial stages of development and schematic indicating relationship between macula densa precursors and mature derivatives. MD: macula densa. CLSN: capillary loop stage nephron. Labelling as indicated on fields.