Table 1.

Overview of FcγRs.

Name	FcγRI	FcγRIIa	FcγRIIb	FcγRIIc	FcγRIIIa	FcγRIIIb
CD	CD64	CD32a	CD32b	CD32c	CD16a	CD16b
Gene	FCGR1A	FCGR2A	FCGR2B	FCGR2B	FCGR3A	FCGR3B
Affinity	High	Low to medium	Low to medium	Low to medium	Low to medium	Low to medium
Major role	Activation	Activation	Inhibition	Activation	Activation	Decoy Activation
Human IgG interaction	IgG1, IgG3, IgG4	IgG3, IgG1, IgG2, IgG4	IgG3, IgG1, IgG4	IgG3, IgG1	IgG1, IgG3, IgG4	IgG1, IgG3
Cell type	Monocytes DCs (Neutrophils) (Mast cells) (Macrophages)	Monocytes Neutrophils DCs Macrophages Basophils Eosinophils Mast cells Platelets	B cells Monocytes DCs Macrophages Eosinophils Basophiles (Neutrophils) (Activated T cells)	NK cells Monocytes Neutrophils	NK cells Monocytes (Macrophages) (Activated T cells)	Neutrophils (Basophils)