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. 2021 Aug 18;22(16):8879. doi: 10.3390/ijms22168879

Figure 2.

Figure 2

LRG1 is expressed in pathological vessels of CNVM. Serial CNV membrane sections were analyzed by immunohistochemistry using anti-LRG1, anti-CD34, and anti-α-SMA antibodies. High magnifications of stained sections displayed in the blue rectangles are shown on the right. Arrows indicate blood vessels positive for LRG1. (a) CNV membrane from an anti-VEGFA-naïve eye with LRG1 expression in vessels and myofibroblasts. (b) CNV membrane from an anti-VEGFA-treated eye with LRG1 expression in vessels. Scale bars: 250 μm; 50 μm for magnifications.