Figure 3.

Activated signal transduction pathways in Cignal Finder Reporter Arrays at 24 h after the uptake of ADSC-LPS-exo into HUVECs, compared to those treated with ADSC-exo. The reporter array had 45 inducible transcription factor-responsive constructs, which controlled firefly luciferase reporter gene expression, in duplicate, in a 96-well plate. The Renilla luciferase gene was included in the wells for the normalization of transfection efficiency. (*, a p-value < 0.05 with at least 5-fold expression of the luminescence).