Figure 2.

Binning frequency distribution of SSRI, SNRI, and DNRI, which were prescribed to the study cohort based on their GeneSight^® pharmacogenetics reports. Color codes for respective bins were based on the classification outlined by Jablonski et al. [30]. These are: (i) ‘use as directed’ (no gene-drug interaction detected; annotated by green label in the test report); (ii) ‘use with caution’ (moderate gene-drug interaction and drug may be effective with dose modification; annotated by a yellow label); and (iii) ‘use with increased caution and with more frequent monitoring’ (severe gene-drug interaction that may significantly impact drug safety and/or efficacy; as annotated by a red label).