Table 1.

Summary of the lipid interactions covered in this manuscript.

		Membrane Protein
		Respiratory Complexes	2° Active Transporters	ATP-Dependent Pumps/Transporters	Channels	GPCRs	Other
Lipid entity	Cholesterol		Activity regulation [8,9]	Activity and changes in conformation [10], Modulation of substrate binding affinity [11]	Channel inhibition [12]	Activation [13], Signalling [14,15], Stability [16,17], Allosteric regulation [18], Lower affinity ligand binding [17], Oligomerisation [19,20,21,22,23]
	PA				Activity [24]	Stabilisation [25]
	PE		Dimer formation and function [26], Dimer formation [27], conformer stability [28]		Conformer stabilisation and channel desensitisation [29]	Agonist and antagonist binding affinities [30], Increase G protein coupling [31,32]	Protein assembly [33]
	PC					Dimerisation [34], β-arrestin interaction and function [35], Increase G protein coupling [31]
	PG		Oligomerisation and function [36]		Conformer stabilisation and channel desensitisation [37]	Increase G protein coupling [30,38], Active conformer stability [39], β-arrestin interaction and function [35], Decrease G protein coupling [31]
	PS		Dimer formation [27],			Stabilisation [25], Dimerisation [34], Decrease G protein coupling [31]
	PI		Dimer formation and function [26], Possible stabilisation [27]
	PtdIns(4,5)P2		Possible dimer stabilisation [40,41],		Activation [42,43], Inactive conformer stability [44]	Active conformer stability [25,45], Increase G protein interaction [25], β-arrestin interaction and complex stability [46], Important for G protein recruitment [47]
	Glycolipids and sphingolipids					Ligand binding [48,49], Signalling [48], Allostery [47]
	Cardiolipin	Oligomer stabilisation [50]	Oligomerisation [51], Allosteric regulation [52]
	DHA and unsaturated tails					Active conformer stability [53,54], Increase G protein coupling [53], Partitioning to lipid rafts [55], Oligomerisation [34,56]
	Saturated tails					Dimerisation and function [57]