. 2021 Aug 22;22(16):9044. doi: 10.3390/ijms22169044

Table 1.

Phenotypic and functional characteristics of human and mouse hepatic NK cells and ILC1.

	Phenotypic Markers			Effector Molecules	References
	Mouse	Human
	Mouse	cNK Cells	lrNK Cells
NK cells	NK1.1⁺, NKp46⁺, CD49a⁻, Eomes⁺, T-bet⁺, CD49b⁺, CD200R⁻, Ly49^+/−, CXCR6⁻, Killer cell lectin-like receptor G1(KLRG1)^+/−, CD62L^+/−	CD56^dim/bright, CD16^bright/low, NKG2D^+/−, NKp46⁺, CD49b⁺, CD49e⁺, CD200R⁻, Eomes⁺, T-bet⁺	CD56⁺, CD16⁻, NKG2D⁺, NKG2C⁺, NKG2A⁻, NKp46⁺, CD49e⁻, CXCR6⁺, CD69⁺, Eomes^hi, T-bet⁻	Granzyme A and B, Perforin, IFN-γ	[55,60,61,62,66,67,68,69,70,71,72]
ILC1	NK1.1⁺, NKp46⁺, CD49a⁺, T-bet⁺, TRAIL⁺, CD49b⁻, CD200R⁺, CD62L⁻, KLRG1⁻, CXCR6⁺, CD127⁺	Lineage⁻CD127⁺CD16⁻NKG2A⁻NKp44⁻CD117⁻		Granzyme B⁺, interleukin (IL)-2, IFN-γ, Tumor necrosis factor (TNF)-α, granulocyte-macrophage colony-stimulating factor (GM-CSF)	[55,57,69,70,71,72,73]