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. 2021 Aug 23;22(16):9092. doi: 10.3390/ijms22169092

Table 2.

CPP classification based on physicochemical properties.

Cell-Penetrating Peptides
Cationic Amphipathic Hydrophobic
Name(origin) Cargo Ref. Name(origin) Cargo Ref. Name(origin) Cargo Ref.
Diatos Peptide Vectors (DPV) siRNA [60] MPG pDNA
siRNA
[61,62] C105Y pDNA [63,64,65,66]
HIV-1 twinarginine translocation (TAT) pDNA
siRNA
[67,68,69,70,71,72,73,74] Transportan pDNA
siRNA
[72,75,76] K-FGF pDNA [77]
arginine-rich peptides pDNA siRNA [78,79,80,81,82] NickFect (NF) pDNA
siRNA
[83,84,85,86] Bip pDNA [87]
Polyarginine pDNA [75,76,88,89,90] PepFect (PF) pDNA
mRNA
[91,92] Melittin-derived peptides siRNA [93]
Penetratin pDNA [94,95,96] MAP siRNA [97]
L5a pDNA [98,99] Crotamine pDNA [100,101,102]
VP22 pDNA [103,104]
Protamine pDNA
mRNA
[105,106,107,108,109] Antennapedia (Antp) AON
siRNA
[110,111]
Pep-1 pDNA [112,113]
CADY siRNA [114,115,116]
FGF pDNA [77]
pVEC pDNA [117,118]