Table 4. Odds ratio (OR) for some the SNPs associated with a positive ELISA-tissue PCR-tissue culture diagnosis (+/-)(P < 5 x 10−7).
| Phenotype | BTA | SNP position | SNP ID | Genotype | Cases (%) | Controls (%) | OR (95% CI) |
|---|---|---|---|---|---|---|---|
| ELISA Tissue PCR Tissue Culture (+/-) | 23 | 15,594,386 | CCATGGGGT/CCATGGGGT | 29 (52.7) | 566 (86.0) | 1.0 | |
| C/CCATGGGGT | 24 (43.6) | 89 (13.5) | 4.7 (2.6–8.5) | ||||
| C/C | 2 (3.6) | 3 (0.5) | 17.5 (2.6–118.3) | ||||
| 23 | 19,329,213 | rs209106537 | C/C | 20 (36.4) | 461 (70.1) | 1.0 | |
| A/C | 25 (45.5) | 181 (27.5) | 3.2 (1.7–5.9) | ||||
| A/A | 10 (18.2) | 16 (2.4) | 13.2 (5.2–33.2) | ||||
| 23 | 22,401,117 | rs385614395 | G/G | 33 (60.0) | 578 (87.8) | 1.0 | |
| C/G | 18 (32.7) | 78 (11.9) | 3.8 (2.0–7.2) | ||||
| C/C | 4 (7.3) | 2 (0.3) | 43.3 (7.5–249.9) | ||||
| 23 | 11,900,592 | rs136621504 | G/G | 37 (67.3) | 607 (92.2) | 1.0 | |
| A/G | 18 (32.7) | 51 (7.8) | 5.5 (2.9–10.4) | ||||
| 5 | 35,577,195 | rs110029938 | T/T | 36 (65.5) | 583 (89.1) | 1.0 | |
| C/T | 17 (30.9) | 71 (10.8) | 4.2 (2.2–8.0) | ||||
| C/C | 2 (3.6) | 1 (0.2) | 44.1 (3.6–538.5) |
(+/-) Animals were considered cases when they were positive to all the tests and controls when they were negative to all of them.