Table 1.
Comparison between migraine patients with and without sleep disorder according to CSHQ’s and SDSC’s scores.
| Feature | Total | Sleep Disorder | Non-Sleep Disorder | p |
|---|---|---|---|---|
| Mean ± SD; Median | Mean ± SD; Median | Mean ± SD; Median | ||
| Age in years | 12.1 ± 3.6; 12.4 | 11.7 ± 3.6; 12.1 | 13.1 ± 3.4; 13.3 | 0.033 |
| Age at migraine onset in years | 7.4 ± 3.6; 7.5 | 7.1 ± 3.7; 7.2 | 8.3 ± 3.4; 8.0 | NS |
| Sex | % (Number) | % (Number) | % (Number) | |
| Males | 38.6 (54) | 39.2 (40) | 36.8 (14) | |
| Females | 61.4 (86) | 60.8 (62) | 63.2 (24) | NS |
| Type of migraine | ||||
| Migraine without aura | 89.3 (125) | 89.2 (91) | 89.5 (34) | |
| Migraine with aura | 10.7 (15) | 10.8 (11) | 10.5 (4) | NS |
| Episodic migraine | 92.9 (130) | 94.1 (96) | 89.5 (34) | |
| Chronic migraine | 7.1 (10) | 5.9 (6) | 10.5 (4) | NS |
| Manifestations of migraine | ||||
| Phonophobia | 65.0 (91) | 66.7 (68) | 60.5 (23) | NS |
| Photophobia | 67.1 (94) | 67.6 (69) | 65.8 (25) | NS |
| Nausea | 49.3 (69) | 51.0 (52) | 44.7 (17) | NS |
| Vomiting | 26.4 (37) | 22.5 (23) | 36.8 (14) | NS |
| Vertigo | 33.6 (47) | 39.2 (40) | 18.4 (7) | 0.021 |
| Migraine equivalents | 76.4 (107) | 82.4 (84) | 60.5 (23) | 0.007 |
| Infantile colic | 35.0 (49) | 33.3 (34) | 39.5 (15) | NS |
| Recurrent gastrointestinal pain | 26.4 (37) | 29.4 (30) | 18.4 (7) | NS |
| Benign paroxysmal vertigo | 18.6 (26) | 22.5 (23) | 7.9 (3) | 0.047 |
| Cyclic vomiting syndrome | 14.3 (20) | 18.6 (19) | 2.6 (1) | 0.016 |
| Recurrent limb pain | 32.1 (45) | 34.3 (35) | 26.3 (10) | NS |
| Motion sickness | 32.9 (46) | 33.3 (34) | 31.6 (12) | NS |
| Benign paroxysmal torticollis | 3.6 (5) | 3.9 (4) | 2.6 (1) | NS |
| Familiarity for migraine | 90.0 (126) | 90.1 (92) | 89.5 (34) | NS |
| Habitual frequency of attacks | ||||
| ≤2 attacks/week | 80.0 (112) | 78.4 (80) | 84.2 (32) | |
| >2 attacks/week | 20.0 (28) | 21.6 (22) | 15.8 (6) | NS |
| Frequency of attacks in the last 2 months | ||||
| ≤2 attacks/week | 72.8 (102) | 86.3 (88) | 89.5 (34) | |
| >2 attacks/week | 12.9 (18) | 17.5 (14) | 10.5 (4) | 0.031 |
| Severe attacks in the last 2 months | ||||
| ≤2 attacks/week | 96.4 (135) | 95.1 (97) | 100.0 (38) | |
| >2 attacks/week | 3.6 (5) | 4.9 (5) | 0.0 (0) | NS |
| Symptomatic drug intake in the last 2 months | ||||
| ≤2 medications/week | 92.9 (130) | 91.2 (93) | 97.4 (37) | |
| >2 medications/week | 7.1 (10) | 8.8 (9) | 2.6 (1) | NS |
| Efficacy of current acute medications | ||||
| Effective | 60.7 (85) | 54.9 (56) | 76.3 (29) | |
| Partially effective | 35.0 (49) | 39.2 (40) | 23.7 (9) | |
| Ineffective | 4.3 (6) | 5.9 (6) | 0.0 (0) | 0.045 |
| Ongoing prophylactic treatments | 15.0 (21) | 17.6 (18) | 7.9 (3) | NS |
| Neuropsychiatric comorbidities | 32.9 (46) | 38.2 (39) | 18.4 (7) | 0.026 |
| Anxiety or mood disorders | 25.0 (35) | 30.4 (31) | 10.5 (4) | 0.016 |
| Systemic comorbidities | 18.6 (26) | 19.6 (20) | 15.8 (6) | NS |
| Chronic pharmacological therapy | 13.6 (19) | 16.7 (17) | 5.3 (2) | NS |
Abbreviations: NS: Non significant; SD: Standard Deviation.