Table 2.

Odds ratios of each thyroid disease for COVID-19 infection in all participants.

Characteristics	COVID-19	Control	ORs (95% Confidence Interval) for COVID-19
	(Exposure/Total, %)	(Exposure/Total, %)	Crude †	p-Value	Model 1 †,‡	p-Value	Model 2 †,§	p-Value	Model 3 †,‖	p-Value
Hypothyroidism	284/8070 (3.5%)	980/32,280 (3.0%)	1.17 (1.02–1.34)	0.025 *	1.11 (0.97–1.28)	0.126	1.12 (0.97–1.29)	0.120	1.09 (0.95–1.26)	0.229
Hyperthyroidism	134/8070 (1.7%)	531/32,280 (1.6%)	1.01 (0.83–1.22)	0.922	1.00 (0.82–1.21)	0.983	0.98 (0.81–1.20)	0.871	N/A
Graves’ disease	20/8070 (0.2%)	97/32,280 (0.3%)	0.82 (0.51–1.34)	0.432	0.82 (0.51–1.33)	0.423	N/A		0.79 (0.49–1.29)	0.348
Thyroiditis	108/8070 (1.3%)	423/32,280 (1.3%)	1.02 (0.83–1.27)	0.844	1.01 (0.81–1.25)	0.930	0.98 (0.78–1.23)	0.840	N/A
Autoimmune thyroiditis	52/8070 (0.6%)	155/32,280 (0.5%)	1.35 (0.98–1.85)	0.065	1.32 (0.96–1.82)	0.085	N/A		1.27 (0.92–1.77)	0.146

CCI: Charlson comorbidity index; N/A: not applicable. * Conditional logistic regression, significance at p < 0.05. † Models were stratified by age, sex, and income. ‡ Model 1 was adjusted for CCI scores and hypertension. § Model 2 was adjusted for model 1 plus hypothyroidism, hyperthyroidism, and thyroiditis. ‖ Model 3 was adjusted for model 1 plus hypothyroidism, Graves’ disease, and autoimmune thyroiditis.