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. 2021 Aug 11;10(16):3522. doi: 10.3390/jcm10163522

Table 4.

Odds ratios of each thyroid disease for mortality in COVID-19 participants.

Characteristics Dead Participants Survived Participants ORs (95% Confidence Interval) for Mortality
(Exposure/Total, %) (Exposure/Total, %) Crude p-Value Model 1 † p-Value Model 2 ‡ p-Value Model 3 § p-Value
Hypothyroidism 6/237 (2.5%) 278/7833 (3.5%) 0.71 (0.31–1.60) 0.406 0.48 (0.19–1.20) 0.115 0.51 (0.20–1.28) 0.152 0.51 (0.20–1.27) 0.147
Hyperthyroidism 4/237 (1.7%) 130/7833 (1.7%) 1.02 (0.37–2.78) 0.973 1.69 (0.55–5.17) 0.359 2.32 (0.74–7.30) 0.152 N/A
Graves’ disease 1/237 (0.4%) 19/7833 (0.2%) 1.74 (0.23–13.07) 0.589 5.77 (0.70–47.74) 0.104 N/A 11.43 (1.29–101.22) 0.029 *
Thyroiditis 0/237 (0.0%) 108/7833 (1.4%) N/A N/A N/A N/A
Autoimmune thyroiditis 0/237 (0.0%) 52/7833 (0.7%) N/A N/A N/A N/A

CCI: Charlson comorbidity index; N/A: not applicable. * Unconditional logistic regression model, significance at p < 0.05. † Model 1 was adjusted for age, sex, income, CCI scores, and hypertension. ‡ Model 2 was adjusted for model 1 plus hypothyroidism, hyperthyroidism, and thyroiditis. § Model 3 was adjusted for model 1 plus hypothyroidism, Graves’ disease, and autoimmune thyroiditis.