Table 4.
Comparison of immunophenotype responses to radical prostatectomy performed by the open or laparoscopic technique.
| Open Radical Prostatectomy | ||||
|---|---|---|---|---|
| Subset | PreOp (Cells/µL) Median (Range) |
Three Months (Cells/µL) Median (Range) | p Value | Trend |
| CD3+ | 1280 (878–2086) | 1538 (924–1956) | 0.84 | ≈ |
| CD4+ | 826 (549–1400) | 839 (630–1162) | 0.72 | ≈ |
| CD8+ | 554 (298–928) | 711 (423–958) | 0.15 | ≈ |
| Ratio CD4+/CD8+ | 1.7 (1.2–2.4) | 1.5 (0.8–2.0) | 0.07 | ≈ |
| CD8+CD69+ | 169 (92–347) | 198 (159–261) | 0.26 | ≈ |
| Ratio CD4+/CD8+CD69+ | 4.5 (2.9–6.9) | 4.3 (3.0–7.0) | 0.16 | ≈ |
| CD4+CD25+FoxP3+ | 3.4 (2.1–6.8) | 3.5 (2.1–4.8) | 0.30. | ≈ |
| CD3-CD16+CD56+ | 205 (106–329) | 294 (170–441) | 0.03 | ↑ |
| MDSC | 11.1 (4.7–16.0) | 14.8 (10.5–26.1) | <0.01 | ↑ |
| CD19+ | 188 (124–299) | 180.735 (147–272) | 0.74 | ≈ |
| Laparoscopic Radical Prostatectomy | ||||
| Subset |
PreOp (Cells/µL)
Median (Range) |
Three Months (Cells/µL) Median (Range) | p Value | Trend |
| CD3+ | 1292 (964−1867) | 1346 (1126–1984) | <0.05 | ↑ |
| CD4+ | 780 (651–1282) | 881 (696–1187) | 0.46 | ≈ |
| CD8+ | 538 (379–780) | 576 (437–904) | <0.001. | ↑ |
| Ratio CD4+/CD8+ | 1.8 (1.1–2.4) | 1.7 (0.9–2.3) | 0.10 | ≈ |
| CD8+CD69+ | 209 (131–330) | 216 (152–322) | 0.15 | ≈ |
| Ratio CD4+/CD8+CD69+ | 4.0 (2.7–6.1) | 4.2 (3.0–6.3) | 0.10 | ≈ |
| CD4+CD25+FoxP3+ | 2.37 (1.1–4.6) | 2.5 (1.2–4.1) | 0.91 | ≈ |
| CD3-CD16+CD56+ | 223 (117–353) | 359 (199–502) | <0.001 | ↑ |
| MDSC | 11.0 (6.4–14.9) | 11.2 (7.4–21.7) | 0.16 | ≈ |
| CD19+ | 187 (119–307) | 185 (131–273) | 0.50 | ≈ |
Symbols in Table 4: “≈”—no significant change; “↑”—increase.