Table 1.

PICOS framework to identify eligibility criteria.

Population:	Adolescent or adult humans with addictive disorders (SUD or other addictive behaviors) or daily/heavy use
Intervention *:	Immersive VR (using Head-Mounted Display) for the assessment or treatment of addictive disorders
Comparators *:	No limitation
Outcomes:	Assessment:        Diagnosis, disease severity, measure of treatment        effect, or predictor of treatment outcome, related        to VR-cue-reactivity (e.g., craving, psychophysio-logical response and attention to cues) Treatment:        Cue-reactivity, motivation, dependence severity,        substance use, abstinence
Study designs:	No limitation, except single case studies (n < 3)
Timing:	No restriction
Language:	English

* Does not apply to the (1) research question focusing on assessment.