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(a) Transmission electron micrograph of a large granular BmVIII-SCC cell on day 85 of culture in a bioreactor with gelatinous beads showing perinuclear strands of rough endoplasmic reticulum (RER) within the cytoplasm and membrane-bound vesicles (ENDO), with disrupted nuclear membrane (NM). (b) Organized RER showing multiple small vesicles.
