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. 2021 Aug 13;10(16):3559. doi: 10.3390/jcm10163559

Table 6.

Univariate survival analysis.

Kaplan Meier
OS RFS
Age 0.329 0.334
Gender 0.336 0.097
ASA classification 0.723 0.317
Preoperative biopsy 0.388 0.515
Preoperative therapy 0.886 0.053
Major resection 0.072 0.065
Extended resection 0.040 0.039
Vascular extension 0.290 0.326
Visceral extension 0.024 0.020
Vascular infiltration 0.018 0.538
Visceral infiltration 0.004 0.079
Morbidity 0.920 0.846
Severe morbidity (≥Clavien-Dindo 3a) [11] 0.822 0.764
Tumor size (<5 vs. 5–10 vs. >10 cm) * <0.001 <0.001
Solitary vs. multifocal tumors 0.149 0.001
T stage <0.001 <0.001
N stage <0.001 0.001
M stage 0.001 <0.001
L stage 0.534 0.702
V stage 0.053 0.301
Pn stage 0.003 0.053
R stage 0.197 0.207
Grading 0.344 0.598
UICC stage <0.001 <0.001

For survival analyses perioperative deaths (n = 18) were excluded; for multivariate analysis, p-values < 0.1 were further analyzed in Table 7 (parameters underlined); significant p-values <0.05 are bold; * size of the largest nodule obtained out of the histology report; UICC stage was not included in multivariate analysis; ASA = American Society of Anesthesiologists.