Table 2.
Studies about the effect of the antioxidant compounds on the wound healing process.
| Compound | Author | Year | Carrier | Type of Study | ||
|---|---|---|---|---|---|---|
| In Vitro | Animal Model | Human | ||||
| Curcumin | Merrell [21] | 2009 | Polycaprolactone nanofibers | X | X | |
| Liu [41] | 2018 | Gelatin microspheres | X | X | ||
| Gong [42] | 2013 | Hydrogel | X | X | ||
| Kant [43] | 2014 | X | ||||
| Pandey [44] | 2020 | Polyvinyl pyrrolidone nanofibers | X | X | ||
| Curcumin + Chitosan | Zhao [19] | 2019 | β-cyclodextrin | X | X | |
| Abbas [45] | 2019 | X | ||||
| Mei [46] | 2017 | Nanofibers polypropylene | X | X | ||
| Curcumin + N-acetyl-cysteine | Castro [47] | 2015 | Galactomannan | X | X | |
| Castro [48] | 2017 | Galactomannan | X (Obs) | |||
| Jimenez-Garcia [49] | 2018 | Galactomannan | X (Obs) | |||
| Jimenez-Garcia [50] | 2021 | Galactomannan | X (Obs) | |||
| N-acetyl cysteine + α-tocopherol | Dhall [51] | 2014 | X | X | ||
| Li [52] | 2020 | Microbiota | X | |||
| N-acetyl cysteine | Ozkaya [23] | 2019 | X | |||
| Oguz [53] | 2015 | X | ||||
| Tsai [24] | 2014 | X | X | |||
| Aktunc [54] | 2010 | X | X | |||
| Hou [55] | 2019 | polycaprolactone | X | X | ||
| Hou [56] | 2020 | polyamide | X | X | ||
| Chitosan | Jiahui [57] | 2020 | polycaprolactone | X | X | |
| Zhang [58] | 2018 | hydrogel poly (γ-glutamic acid) and heparin | X | X | ||
| Liu [29] | 2018 | catechol-modified chitosan film | X | X | ||
| Zhao [59] | 2017 | Hydrogel (polyaniline) | X | X | ||
| Mo [60] | 2015 | X (Exp) | ||||
| Halim [61] | 2018 | X (Exp) | ||||
| Chitosan + plan extracts | Colobatiu [27,28] | 2019 | Polymer and polyvinyl alcohol | X | X | |
| Rocasalbas [62] | 2013 | Gelatin hydrogel | X | |||
| Díaz-González [63] | 2012 | X | ||||
| Bektas N [64] | 2020 | Hydrogel | X | X | ||
| Chitosan + gallic acid | Thi [31] | 2020 | Gelatin hydrogel | X | X | |
| Singh [65] | 2019 | X | ||||
| Yang [66] | 2016 | X | ||||
| Stefanov [30] | 2016 | X | X (ExV) | |||
| Edaravone | Fan [32] | 2019 | Alginate hydrogel | X | X | |
| Naito [67] | 2014 | X | ||||
| Crocin and Safranal | Zeka [68] | 2017 | hydrogel | X | ||
| Khorasani [34] | 2008 | X | ||||
| Alemzadeh [35] | 2018 | X | ||||
| Quercetin | Ajmal [69] | 2019 | poly (e-caprolactone) | X | ||
| Ajmal [70] | 2019 | poly (e-caprolactone) | X | |||
| Tran [38] | 2019 | X | ||||
| Gomathi [39] | 2002 | X | ||||
| Yin [40] | 2018 | X | ||||
| Kant [71] | 2020 | X | ||||
| Quercetin + Oleic acid | Gallelli [72] | 2020 | X (Exp) | |||
X: Type of study; Exp: Experimental; ExV: Ex Vivo; Obs: Observational.