Table 1.
Statistically significant differences found by optical coherence tomography parameters analyzed at weeks 8, 12 and 24.
| Time | OCT Protocol | Sector | ONT (Mean ± SD in μm) | OHT (Mean ± SD in μm) | D% | p * | OHT Groups (Mean ± SD in μm) | p † | |
|---|---|---|---|---|---|---|---|---|---|
| 8 W | R | Central | 277.20 ± 17.86 | 263.21 ± 22.03 | −5.05 | 0.022 | MS | 263.80 ± 22.89 | 0.022 |
| ES | 260.30 ± 17.86 | ||||||||
| Temporal Inner | 244.70 ± 8.35 | 251.90 ± 18.50 | +2.86 | 0.047 | MS | 250.78 ± 14.82 | 0.047 | ||
| ES | 257.50 ± 31.74 | ||||||||
| Inferior Outer | 239.90 ± 6.19 | 250.50 ± 11.13 | +4.23 | 0.003 | MS | 251.40 ± 11.34 | 0.003 | ||
| ES | 246.00 ± 9.30 | ||||||||
| Nasal Outer | 243.30 ± 4.34 | 253.60 ± 12.85 | +4.06 | 0.002 | MS | 253.96 ± 11.84 | 0.002 | ||
| ES | 251.90 ± 17.60 | ||||||||
| Superior Outer | 246.30 ± 4.19 | 256.86 ± 17.28 | +4.13 | 0.017 | MS | 257.04 ± 16.69 | 0.017 | ||
| ES | 256.00 ± 20.89 | ||||||||
| Temporal Outer | 245.00 ± 6.48 | 254.10 ± 16.10 | +3.58 | 0.013 | MS | 253.12 ± 12.17 | 0.013 | ||
| ES | 259.00 ± 29.37 | ||||||||
| GCL | Central | 19.80 ± 3.39 | 17.03 ± 3.34 | −13.99 | 0.014 | MS | 16.78 ± 3.27 | 0.014 | |
| ES | 18.30 ± 3.62 | ||||||||
| Superior Inner | 24.10 ± 1.85 | 20.91 ± 4.03 | −13.24 | 0.004 | MS | 20.53 ± 4.04 | 0.004 | ||
| ES | 22.80 ± 3.61 | ||||||||
| 12 W | R | Central | 285.33 ± 18.90 | 266.00 ± 16.73 | −6.76 | 0.039 | MS | 267.33 ± 17.21 | 0.039 |
| ES | 265.56 ± 17.61 | ||||||||
| 24 W | RNFL | Nasal Superior | 39.27 ± 7.25 | 28.88 ± 11.99 | −26.46 | 0.036 | MS | 31.00 ± 10.66 | 0.050 |
| ES | 27.60 ± 13.10 |
OCT: optical coherence tomography; R: retina; GCL: ganglion cell layer complex; RNFL: retinal nerve fiber layer; W: week; ONT: ocular normotension cohort; OHT: ocular hypertension cohort; ES: episcleral sclerosis group; MS: microspheres group; D%: differences in percentage; p: statistical differences (<0.05): * U Mann Whitney; † Kruskal Wallis; the lowest thickness values are highlighted in bold.