Table 1.

Comparison of hub gene expression profiles of interesting modules in the response of SARS-CoV-2, RSV, IAV, and IAV-ΔNS1.

Cell Line	Selected Module	Hub Genes	SARS-CoV-2		RSV		IAV		IAV-ΔNS1
			logFC	p-Value	logFC	p-Value	logFC	p-Value	logFC	p-Value
A549	Turquoise	MX1	5.06	3.08 × 10−168	5.54	1.76 × 10−110	−4.46	ns	-	-
		IFI6	4.29	5.12 × 10−274	2.92	5.97 × 10−43	−0.57	ns	-	-
		IFIT1	3.76	4.33 × 10−163	5.09	7.98 × 10−105	0.03	ns	-	-
		IFIT3	1.97	5.28 × 10−44	4.99	4.88 × 10−101	0.34	ns	-	-
		OAS1	1.55	2.74 × 10−68	3.10	8.42 × 10−51	0.75	0.006989	-	-
		OAS3	1.39	3.43 × 10−57	2.98	1.27 × 10−47	−0.02	ns	-	-
		ISG15	4.33	2.78 × 10−157	4.52	5.05 × 10−88	−0.80	ns	-	-
		DDX60	2.30	4.77 × 10−46	3.10	1.61 × 10−38	−0.06	ns	-	-
		IRF9	2.16	1.57 × 10−84	1.33	1.61 × 10−9	0.46	ns	-	-
		PARP9	2.07	1.14 × 10−75	3.02	6.60 × 10−43	0.42	ns	-	-
NHBE	Yellow-green	IL36G	2.72	1.08 × 10−57	-		0.88	0.004286	4.12	7.63 × 10−20
		SAA2	2.41	1.77 × 10−78	-	-	0.74	4.02 × 10−7	2.69	4.02 × 10−07
		TNIP1	1.26	1.63 × 10−37	-	-	0.01	ns	1.46	9.28 × 10−8
		TNFAIP3	1.61	2.64 × 10−49	-	-	1.41	4.55 × 10−16	4.49	1.47 × 10−22
		HEPHL1	1.30	2.82 × 10−18	-	-	1.45	5.47 × 10−8	1.56	1.86 × 10−5
		IRAK2	1.60	2.89 × 10−22	-	-	0.97	1.25 × 10−5	2.86	3.05 × 10−23
		HBEGF	1.29	1.07 × 10−30	-	-	1.09	0.005477	2.07	8.60 × 10−24
		LIF	1.30	4.01 × 10−31	-	-	0.17	ns	2.89	4.10 × 10−9
		IRF9	1.25	3.69 × 10−29	-	-	1.39	9.52 × 10−10	2.75	3.45 × 10−43
		IL1B	1.06	7.22 × 10−25	-	-	−0.04	ns	1.24	5.98 × 10−9
		IL8	2.32	9.20 × 10−96	-	-	-	-	-	-
		PGLYRP4	2.02	9.89 × 10−23	-	-	1.08	0.088695	1.98	0.004146