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. 2021 Aug 27;7(35):eabe3771. doi: 10.1126/sciadv.abe3771

Fig. 2. Kinetics of HIF target gene expression and dependence on PADI4 in SUM159 cells.

Fig. 2

(A to D) NTC and PADI4-knockdown subclones (shPADI4 #4 and #5) were exposed to 20 or 1% O2 for 5 to 48 hours and analyzed by RT-qPCR for ANGPTL4 (A), VEGFA (B), PGF (C) or RPL13A (D) mRNA expression. Data are shown as mean ± SEM (n = 3). ###P < 0.001 versus NTC at 20% O2; ***P < 0.001 versus NTC at 1% O2 (two-way ANOVA).