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. 2021 Jul 12;1(8):1275–1287. doi: 10.1021/jacsau.1c00201

Table 1. Reactivity of Sera from L. major Infections, Heterologous Diseases, and L. tropica Infections with NGP27b, NGP28b, and NGP30b.

    NGP27b
 NGP28b
 NGP30b
infection/disease n positive negative positive negative positive negative
Original Valuesa
L. major 81 77 4 70 11 73 8
heterologous 24 5 19 6 18 6 18
L. tropica 15 1 14 2 13 4 11
Post-TG-ROC Analysisb
L. major 81 76 5 65 16 70 11
heterologous 24 4 20 7 17 0 24
L. tropica 15 0 15 3 12 1 14
a

Values calculated based on the initial cutoff value (Ci ; titer = 1.000) (Figure 2a), as described in the Supporting Information (“Chemiluminescent ELISA”).

b

Values calculated based on the TG-ROC analysis (Figure 2c; Tables S1 and S2).