Table 2. Mutations of the H1pdm09 defining the sequences of the Sw-L cluster of the H1pdm09 phylogenetic tree (Figure 3).
Positions in the aa sequences are numbered from the first methionine. Bold letters indicate the mutations that are unique to the Danish swine divergent cluster. RBS: receptor binding site.
| Aa change Hu-L → Sw-L | Prevalence in the Sw-L cluster | Prevalence outside the Sw-L cluster | Antigenic site/RBS |
|---|---|---|---|
| N/S16D | 44/46 | 0/75 | - |
| N/D114N/H | 46/46 | 39/75 | - |
| P141T | 46/46 | 0/75 | Sa |
| N/G/K142D | 45/46 | 15/75 | Sa |
| H143N/D/E | 46/46 | 0/75 | Sa |
| D144N/K | 42/46 | 0/75 | - |
| S145L | 41/46 | 0/75 | - |
| N/S/D146K/E | 46/46 | 0/75 | RBS |
| N/Q/K147E | 46/46 | 1/75 | RBS |
| A152S | 46/46 | 2/75 | RBS |
| N/K/R159S | 45/46 | 1/75 | Ca1/RBS |
| G/E/R/V172T/M | 46/46 | 0/75 | Sa |
| N/S/K173D/G | 44/46 | 0/75 | Sb |
| K/E/A/Q180I | 46/46 | 0/75 | Sa |
| D185N | 39/46 | 0/75 | Ca1 |
| T/S/N/D202A | 44/46 | 0/75 | - |
| S/T/W/E207R | 42/46 | 3/75 | Sb/RBS |
| D239N | 46/46 | 4/75 | Ca2/RBS |
| K/T/E319Q | 46/46 | 0/75 | - |
| I/V/T338D | 42/46 | 0/75 | - |