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. 2021 Jul 1;18(8):2986–2996. doi: 10.1021/acs.molpharmaceut.1c00193

Table 9. Release Constants (K) and Correlation Coefficients (R2) Determined by Mathematical Models.

  0-order release
I-order release
HiguChi model
Korsmeyer–Peppas model
sample K0 ± SDa R2 KI ± SD R2 KH ± SD R2 KKP ± SD R2
MP PLA/PVA-AMI 0.262 ± 0.039 0.9457 0.388 ± 0.082 0.7340 0.245 ± 0.031 0.9740 0.564 ± 0.046 0.9973
MP PLA–PEG/PVA-AMI 0.324 ± 0.014 0.8859 0.539 ± 0.040 0.8158 0.300 ± 0.013 0.9566 0.631 ± 0.028 0.9996
a

SD—three independently prepared material samples, analyzed three times.