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. 2021 Aug 12;12:711902. doi: 10.3389/fendo.2021.711902

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Copyright © 2021 Li, Zhang, Zheng, Tian, Zhang, Tan, Li, Zhang and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exosomes improved reproductive functions of POI mice. (A) Representative outcomes of reproduction in the three groups. (B) Pregnancy rate at 4 weeks after treatment. (C) Cumulative pregnancy rate at 8 weeks after treatment. (D) The number of offspring in the three groups. (E) Time to birth after treatment. Data are presented as percentage or mean ± SD; n = 6 per group; *p < 0.05, **p < 0.01, ***p < 0.001; ns, no significance.