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. 2021 Aug 12;9:681790. doi: 10.3389/fcell.2021.681790

FIGURE 3.

FIGURE 3

Characteristics of AngII-induced AAA model ultrasonography and baseline. (A) Representative the macroscopic features of abdominal aorta in the four groups. (B) The SBP was measured by tail-cuff weekly in the four groups. Baseline blood pressure was not different. Compared with that on the 0th day, the SBP in the AngII group increased on the 28th day, which was statistically significant (123 ± 3.25 mmHg vs 139 ± 5.83 mmHg, *P < 0.05, two-way ANOVA), while the SBP among the four groups was not statistically significant in the weekly comparison (P > 0.05, two-way ANOVA). n = 5 per group. (C) Percentage of mice in which aortic aneurysm was successfully achieved in the four groups. (D) Representative the ultrasonography images (left) and the data of maximal abdominal aortic diameters (right) in the four groups at the end of 28 days. (E,F) The histological analysis (H&E, EVG, and Masson’s trichrome staining) of abdominal aorta of mice under different treatments for each condition (Scar bar 100 μm). Statistical analysis of collagen deposition. *P < 0.05 vs the Ang II + M5Ab group; **P < 0.05 vs the control and control + M5Ab groups. Abbreviations: H&E, hematoxylin and eosin; and L, lumen. Data are expressed as means ± SEM; n = 3 per group.